Yazar "Bolgen, Nimet" için listeleme
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In vivo performance of simvastatin-loaded electrospun spiral-wound polycaprolactone scaffolds in reconstruction of cranial bone defects in the rat model
Piskin, Erhan; Isoglu, I. Alper; Bolgen, Nimet; Vargel, Ibrahim; Griffiths, Sarah; Cavusoglu, Tarik; Cartmell, Sarah (Wiley, 2009)Reconstruction of large bone defects is still a major problem. Tissue-engineering approaches have become a focus in regeneration of bone. In particular, critical-sized defects do not ossify spontaneously. The use of ... -
Stem cell suspension injected HEMA-lactate-dextran cryogels for regeneration of critical sized bone defects
Bolgen, Nimet; Korkusuz, Petek; Vargel, Ibrahim; Kilic, Emine; Guzel, Elif; Cavusoglu, Tarik; Piskin, Erhan (Taylor & Francis Ltd, 2014)HEMA-Lactate-Dextran cryogel scaffolds were produced by cryogelation. Mesencyhmal stem cells (MSC) were isolated from rat bone marrow. Critical sized cranial bone defects were created in rat cranium. Stem cells were injected ... -
Stem cells combined 3D electrospun nanofibrous and macrochannelled matrices: a preliminary approach in repair of rat cranial bones
Isoglu, Ismail Alper; Bolgen, Nimet; Korkusuz, Petek; Vargel, Ibrahim; Celik, Hakan Hamdi; Kilic, Emine; Piskin, Erhan (Taylor & Francis Ltd, 2019)Repair of cranial bone defects is an important problem in the clinical area. The use of scaffolds combined with stem cells has become a focus in the reconstruction of critical-sized bone defects. Electrospinning became a ... -
Tissue responses to novel tissue engineering biodegradable cryogel scaffolds: An animal model
Bolgen, Nimet; Vargel, Ibrahim; Korkusuz, Petek; Guzel, Elif; Plieva, Fatima; Galaev, Igor; Piskin, Erhan (Wiley, 2009)Biodegradable macroporous cryogels with highly open and interconnected pore structures were produced from dextran modified with oligo L-lactide bearing hydroxyethylmethacrylate (HEMA) end groups in moderately frozen ...